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Difficulties with BoNT use in ophthalmology crop up because of toxin diffusion or inadvertent placement in the adjacent muscles. Ptosis from the eyelid is the most typical complication of BoNT treatment of strabismus and blepharospasms.23 Whilst this effect is nearly always momentary and self-resolving, apraclonidine 0.five% (Iopidine) or phenyleph